Monday, 22 October, 2018

Mom was taking viagra during pregnancy: 11 babies died in the Netherlands

A hospital in Amsterdam said it is immediately stopping a drug trial where pregnant moms were given sildenafil to help with underdeveloped babies. Eleven of the babies in the trial died Dutch drug trial for pregnant moms stopped after 11 babies die Babies die after Dutch
Ben Pena | 28 July, 2018, 08:14

Another 10 to 15 pregnant women who took sildenafil as part of the trial are now waiting to discover if their baby has been adversely affected.

"The chance of a disease of the blood vessels of the lungs appears to be greater and the chance of death after birth seems to have increased", the statement read.

The research was carried out at 10 hospitals across the Netherlands and involved women whose placentas had been underperforming.

Pills of the drug Viagra (L) made by Pfizer, are shown in this file photo in NY.

But the results showed that 17 babies were born with lung conditions and 11 died. Nine other babies born to women in the control group died of unrelated problems.

'All adverse effects occurred after birth.

"We have already notified Canadian researchers who are conducting a similar study", Ganzevoort said.

Among the women taking Sildenafil, 11 of the babies died due to "a possibly related lung condition" that caused high blood pressure in the lungs and may have resulted from reduced oxygen levels.

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The Queensland study was used over a significantly shorter time frame and for different reasons, but it had been paused as a precautionary measure while he gathered more information from the Dutch researchers, he added. It can lead to stillbirth or neonatal death, and babies that survive are still at higher risk for infections and often suffer from long-term problems such as obesity and cardiovascular disease.

In total, 93 women were given sildenafil while the remaining 90 were given a dummy drug or placebo. In any case, they have temporarily stopped their research'.

As a result, the researchers at the University of British Columbia have also suspended a clinical trial called STRIDER.

It can mean babies are born prematurely, with a very low birth weight and poor chances of survival.

But she supports the decision made by Dutch investigators to discontinue to the study. The doctors decided that the child would be better to stay and develop inside the mother.

Huf-Germain said she did not recall being told of any risks to her child at the start of the trial, but such was the desperation of the women involved that few would have comprehended the possible consequences. Viagra is known to dilate some blood vessels, including those in the penis-which is how it became a blockbuster drug for erectile dysfunction-and a number of animal studies and small human trials suggested the drug might benefit unborn children.

"It needs a thorough investigation because the complications were not seen in the two other, similar trials that have already been done in the United Kingdom and Australia and New Zealand".

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